WebSep 3, 2010 · A new class of specific breast cancer resistance protein (BCRP) inhibitors was identified, showing no inhibition of the ATP binding cassette (ABC) transporters P-gp and MRP1. Some of these modulators inhibit BCRP with high potency; they are only slightly less potent than Ko143 and could serve as pro … This protein is a member of the White subfamily. Alternatively referred to as the breast cancer resistance protein (BCRP), this protein functions as a xenobiotic transporter which may play a role in multi-drug resistance to chemotherapeutic agents including mitoxantrone and camptothecin analogues. See more ATP-binding cassette super-family G member 2 is a protein that in humans is encoded by the ABCG2 gene. ABCG2 has also been designated as CDw338 (cluster of differentiation w338). ABCG2 is a translocation … See more • ATP-binding cassette transporter See more • Hazai E, Bikádi Z (April 2008). "Homology modeling of breast cancer resistance protein (ABCG2)". Journal of Structural Biology. 162 (1): … See more The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. … See more It is inhibited by some calcium channel blockers such as amlodipine, felodipine and nifedipine. The fungal toxin fumitremorgin C (FTC) inhibits the protein but has neurotoxic side … See more • ABCG2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Human ABCG2 genome location and See more
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WebList of Roblox employees Roblox Wiki Fandom in: Lists List of Roblox employees View source This article is about the employees on Roblox.com. For the staff of this wiki, please see RW:STAFF. This page contains a list of all Roblox employees, including administrators, interns, accelerators, incubators, and former accelerators and incubators. WebABCG2. A gene on chromosome 4q22, which encodes a xenobiotic transporter protein of the ATP-binding cassette (ABC) superfamily, White subfamily. It plays a major role in … homelessness in san bernardino ca
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WebBcrp (breast cancer resistance protein), mouse. Gene name: ATP-binding cassette, sub-family G, member 2 (Abcg2) Like their human counterpart, rodent orthologues of BCRP are ATP-binding cassette half-transporters with a broad range of endogenous and xenobiotic substrates. The rodent Bcrp gene is located on chromosome 6, at a distance of 2829cM ... WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. WebBCRP is capable of transporting non-chemotherapy drugs and xenobiotiocs as well, including nitrofurantoin, prazosin, glyburide, and 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine. BCRP is frequently detected at high levels in stem cells, likely providing xenobiotic protection. BCRP is also highly expressed in normal human tissues including ... hinckley parks hinckley