Highlights in pathogenesis of vitiligo
WebJun 4, 2015 · A vitiligo-like leukoderma may occur in patients with metastatic melanoma. Vitiligo can also be induced by drugs, such as immune checkpoint inhibitors … WebAug 25, 2024 · Mohammed, G. F. Highlights in pathogenesis of vitiligo. World J. Clin. Cases 3 , 221 (2015). Article PubMed PubMed Central Google Scholar
Highlights in pathogenesis of vitiligo
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WebMay 25, 2024 · Combined, these associations highlight the key players in the contribution of T-cells to the pathogenesis of vitiligo. Other candidate loci for vitiligo in several ethnicities include FASLG , a member of the TNF superfamily, and GZMB, a protease, both of which point to a role of dysregulated apoptosis in vitiligo. WebMay 25, 2024 · Combined, these associations highlight the key players in the contribution of T-cells to the pathogenesis of vitiligo. Other candidate loci for vitiligo in several ethnicities include FASLG , a member of the TNF superfamily, and GZMB, a protease, both of which point to a role of dysregulated apoptosis in vitiligo.
WebJul 1, 2024 · Combined, these associations highlight the key players in the contribution of T-cells to the pathogenesis of vitiligo. Other candidate loci for vitiligo in several ethnicities include FASLG , a member of the TNF superfamily, and GZMB, a protease, both of which point to a role of dysregulated apoptosis in vitiligo. WebMar 1, 2015 · Many theories were elaborated to clarify vitiligo pathogenesis. It is a multifactorial disease involving the interplay of several factors. Future research is needed …
WebJan 6, 2024 · Collectively, the current evidence nominates GzmB as a promising biomarker and therapeutic target in autoimmune skin disease. Figure 1. Current understanding of GzmB in cutaneous autoimmune diseases, including psoriasis, vitiligo, systemic sclerosis, alopecia areata, interface dermatitis, and bullous pemphigoid. Not to scale. WebThe critical role of miRNAs in skin-specific autoimmune diseases that proved to be potential biomarkers for autoimmune skin disorders, warranting their exploration as therapeutic targets, is highlighted. BACKGROUND Psoriasis and vitiligo are both chronic, skin-specific diseases classified as autoimmune diseases due to the involvement of several …
WebJul 29, 2024 · The pathogenesis of vitiligo is still relatively unknown, but associations between vitiligo and other systemic autoimmune diseases have been made, such as with patients who have undergone...
WebFeb 16, 2024 · National Center for Biotechnology Information oouc rnuWebVitiligo is thought to be a skin memory disease because clinical observations show that relapse occurs essentially at the same location as a previously depigmented spot ( … oouc 2022WebApr 26, 2024 · Abstract Vitiligo is an autoimmune disease of the skin that targets pigment-producing melanocytes and results in patches of depigmentation that are visible as white spots. Recent research studies have yielded a strong … ooui wasm tutorialWebNov 17, 2024 · 1 INTRODUCTION. Vitiligo is an autoimmune disease featured as chronic depigmentation and milk-white lesion in the skin with a prevalence of 0.5% of the general population (Figure 1A).Although not accompanied by disturbing senses like pruritus or pain, vitiligo might negatively affect people's self-esteem and even cause anxiety or depression, … ooty winterWebFeb 16, 2024 · Pathophysiology. Vitiligo is commonly known as multifactorial polygenic disorder and has complex pathogenesis. It is commonly associated with both non-genetic and genetic factors. However various theories have been proposed about its pathogenesis but the exact etiology is still unknown. The generally agreed principles are the absence of ... o o\\u0027reilly auto parts storeWebNov 29, 2024 · Vitiligo is a common, acquired, autoimmune, chronic disorder of pigmentation characterized by the development of white macules on the skin due to loss … iowa department of charitable gamblingWebMar 14, 2024 · Vitiligo is a common acquired depigmenting disease characterized by the loss of functional melanocytes and epidermal melanin. Vitiligo has a long treatment cycle and slow results, which is one of the most difficult challenges for skin diseases. Oxidative stress plays an important role as an initiating and driving factor in the pathogenesis of … ooun bourse 2023 resultat