Web1. okt 2008 · The distribution of [ C]VC701, a chloro-derivative of VC195, was also oxodihydropurines, (6) phenoxyarylacetamides and (7) imi- dazopyridines and bioisosteric structures (imidazopyrida- evaluated in healthy rodents, and it was found that PK11195 zines and pyrazolopyrimidines). co-injection affected mostly the peripheral organs [66]. WebNovel pyrazolo[1,5-a]pyrimidines as translocator protein 18 kDa (TSPO) ligands: Synthesis, in vitro biological evaluation, [18F]-labelling and in vivo neuroinflammation PET images
TSPO PET Imaging: From Microglial Activation to Peripheral ... - Hindawi
WebJ. Chen et al. (eds.), Immunological Mechanisms and Therapies in Brain Injuries and Stroke , 235 Springer Series in Translational Stroke Research, DOI 10.1007/978-1-4614-8915-3_13, Web8. feb 2016 · A new fluorine-substituted ligand, compound 1 (CB251), with a very high affinity (Ki = 0.27 ± 0.09 nM) and selectivity for the 18-kDa translocator protein (TSPO), is presented as an attractive biomarker for the diagnosis of neuroinflammation, neurodegeneration and tumour progression. To test compound 1 as a TSPO PET imaging … c# dictionary vs array performance
Recent developments on PET radiotracers for TSPO and their …
Web19. apr 2024 · Introduction: Benzodiazepines, including temazepam are described as TSPO antagonists. In fact, TSPO was initially described as a peripheral benzodiazepine receptor … Web1. apr 2024 · Europe PMC is an archive of life sciences journal literature. Web25. apr 2024 · By [18 F]fluoroalkylation of the phenol precursor with [18 F]fluoroethyl bromide ([18 F]FEtBr), [18 F]VUIIS1018A with 1.4–2.1 GBq was obtained as an injectable solution at the end of synthesis (EOS), starting from 7.4 GBq of cyclotron-produced [18 F]F − ().The decay-corrected radiochemical yield was 33 ± 9% (n = 7) based on [18 F]F − in the … c# dictionary value to key