Phospho-yap1
WebInvitrogen Anti-Phospho-YAP1 (Ser127) Polyclonal, Catalog # PA5-17481. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse, Rat samples. … WebPhospho-YAP1 is retained in the cytoplasm. In the absence of Hippo signaling, YAP1 translocates to the nucleus, associates with co-activators TEAD1-4, and functions as a transcriptional factor promoting the expression of key target genes. Components of the Hippo pathway are mutated in human cancers, and deregulation of this pathway plays a …
Phospho-yap1
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WebMonoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser397 of human YAP protein isoform 1. … WebYAP1 Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein …
WebPhosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell … WebJun 19, 2024 · The transcriptional coactivator YAP1 (yes-associated protein 1) regulates cell proliferation, cell-cell interactions, organ size, and tumorigenesis. ... genetic experiments revealed that intact androgen receptor signaling is necessary for androgen's inactivating effect on phospho-Ser-127 levels and increased YAP1 nuclear entry. We also found ...
WebWB analysis using 29018-1-AP. Serum-free treated NIH/3T3 cells and 10 % fetal bovine serum treated NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 29018-1-AP (Phospho-YAP1 (Ser397) antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. The membrane was stripped and re-blotted with GAPDH … WebMonoclonal Anti-phospho-YAP1 (pTyr357) (mouse IgM isotype) is derived from the hybridoma PYP-76 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic phosphopeptide corresponding to a fragment containing (pTyr357) of human YAP1 conjugated to KLH.
WebNov 30, 2024 · YAP1 Antibody (63.7) is an IgG2a κ mouse monoclonal YAP antibody suitable for the detection of YAP of mouse, rat and human origin by WB, IP, IF, IHC (P) and ELISA. YAP1 Antibody (63.7) is available as the non-conjugated anti-YAP antibody form.
WebAnti-phospho-YAP1 (pTyr357) antibody produced in rabbit has been used in western blotting [ 2] and immunofluorescence. Packaging 25, 100, 200 μL Biochem/physiol … irish built titanicWebDot Blot: Transcriptional coactivator YAP1 (phospho Y357) peptide General notes This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free production porsche of nashville inventoryWebImmunocytochemistry analysis of Phospho-YAP1 (Ser127) in HeLa. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and … irish buried uprightWebPhospho-YAP1 (Ser127) Antibody (MA5-33207) in ICC/IF Immunofluorescence analysis of Transcriptional coactivator YAP1 was performed using 70% confluent log phase Hep G2 … irish burning peatWebOct 2, 2024 · The Hippo pathway effector, Yes-associated protein (YAP), is a transcriptional coactivator implicated in cholangiocarcinoma (CCA) pathogenesis. YAP is known to be regulated by a serine/threonine kinase relay module (MST1/2–LATS1/2) culminating in phosphorylation of YAP at Serine 127 and cytoplasmic sequestration. irish bunsWebJul 23, 2024 · The gene that has received the most attention in the literature is YAP1, which was found to be involved in the development and progression of CRC [ 5, 6, 9, 10 ]. The gene was reported to be overexpressed in 52.5% (73/139) of CRC, and the YAP1 protein was predominantly localized to the nucleus [ 11 ]. porsche of nashville phone numberWebAnti-phospho-YAP1 (pTyr357) antibody produced in rabbit Synonym (s): Anti-YAP, Anti-YAP2, Anti-YAP65, Anti-Yes-associated protein 1, 65kDa Match Criteria: Product Name, Keyword All Photos ( 1) Anti-phospho-YAP1 (pTyr357) antibody, Mouse monoclonal Match Criteria: Product Name, Keyword All Photos ( 25) porsche of nashville - brentwood