Thump domain-containing protein

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August undefined, 2024

WebTHUMP DOMAIN-CONTAINING PROTEIN 2; THUMPD2 Alternative titles; symbols CHROMOSOME 2 OPEN READING FRAME 8; C2ORF8 SAM-DEPENDENT METHYLTRANSFERASE HGNC Approved Gene Symbol: THUMPD2 Cytogenetic location: 2p22.1 Genomic coordinates (GRCh38): 2:39,736,060-39,779,276 (from NCBI) TEXT … WebJan 31, 2024 · As described below, the THUMP domain captures the 3′-end of RNA (in the case of tRNA, the CCA-terminus). This concept is proposed based on structural, biophysical and biochemical studies of ThiI and is extended to studies of other THUMP-related tRNA modification enzymes. 4.1. 4-Thiouridine Synthetase (ThiI)

Multiple sequence alignment of Trm14-like proteins. The positions …

WebHerein, using a reverse genetics approach coupled with RNA-mass spectrometry, we identified that THUMP domain-containing protein 3 (THUMPD3) is responsible for tRNA: … WebThe human and mouse THUMPD2 methyltransferase domains share 82% amino acid identity. Northern blot analysis of human tissues detected 2.0-, 2.1-, and 3.2-kb … salesforce einstein discovery license

CDD Conserved Protein Domain Family: THUMP_ThiI - National …

WebMar 1, 2001 · Protein THUMP domain-containing protein 1 homolog Status UniProtKB reviewed (Swiss-Prot) Organism Drosophila melanogaster (Fruit fly) Amino acids 324 … WebNX_Q9NXG2 - THUMPD1 - THUMP domain-containing protein 1 - Sequence. Functions as a tRNA-binding adapter to mediate NAT10-dependent tRNA acetylation (PubMed:25653167). WebZinc finger (Znf) domains are relatively small protein motifs that bind one or more zinc atoms, and which usually contain multiple finger-like protrusions that make tandem contacts with their target molecule. They bind DNA, RNA, protein and/or lipid substrates. salesforce einstein chat bot

THUMP domain containing 2 protein possibly induces resistance …

Entry - *616662 - THUMP DOMAIN-CONTAINING …

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … WebMar 30, 2006 · Solution structure of the THUMP domain of THUMP domain-containing protein 1. PDB DOI: 10.2210/pdb2DIR/pdb; Classification: RNA BINDING PROTEIN; … salesforce einstein reply recommendationsWebSeven genes, THUMP domain-containing protein 2 (THUMPD2), nuclear factor interleukin-3-regulated protein (NFIL3), tyrosine-protein kinase transmembrane receptor 2 (ROR2), C-X … salesforce einstein analytics growth

"WebTHUMPD2 (THUMP domain-containing protein 2) is a 503 amino acid protein that contains one THUMP domain and belongs to the methyltransferase superfamily. THUMPD2 is expressed in a variety of tissues including brain, colon, gingiva, heart, kidney, liver, lung, placenta, small intestine, spleen and thymus. " - Thump domain-containing protein

Thump domain-containing protein

RCSB PDB - 2DIR: Solution structure of the THUMP domain of THUMP domain …

WebAug 9, 2024 · THUMPD1 functions as an adaptor protein for secondary modification of transfer RNA (tRNA) by cytosine acetylation ( Sharma et al., 2015 ). Cloning and … WebMar 30, 2006 · RCSB PDB - 2DIR: Solution structure of the THUMP domain of THUMP domain-containing protein 1 NMR Ensemble 3D View : Structure 1D-3D View Validation Report Macromolecule Content Total Structure Weight: 10.76 kDa Atom Count: 753 Modelled Residue Count: 98 Deposited Residue Count: 98 Unique protein chains: 1 …

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WebProtein tRNA (guanine (6)-N2)-methyltransferase THUMP3 Gene THUMPD3 Status UniProtKB unreviewed (TrEMBL) Organism Homo sapiens (Human) Amino acids 269 … WebTHUMP There are 21235 THUMP domains in 21235 proteins in SMART's nrdb database. Click on the following links for more information. Evolution (species in which this domain is found) Literature (relevant references for this domain) Structure (3D structures containing this domain) Links (links to other resources describing this domain)

WebThe THUMP (after thiouridine synthases, RNA methylases and pseudouridine synthases) domain is an ancient 100-110 amino acid motif that is found in proteins that are involved in RNA-modification pathways. THUMP domains contain RNA-binding sequences and are thought to deliver RNA modification enzymes to their target substrates. WebProtein [EntityWithAccessionedSequence] Species. Homo sapiens. Compartment. nucleoplasm. Synonyms. THUMP domain-containing protein 1, THUM1_HUMAN ... Synonyms. THUMP domain-containing protein 1, THUM1_HUMAN Locations in the PathwayBrowser Expand all External Reference Information. External Reference …

WebApr 7, 2024 · THUMPD1 protein in knockout cell lines was evaluated by western blots with corresponding cell extracts probed by anti-THUMPD1 antibodies (Bethyl Labs and/or Thermo Fisher Scientific). GAPDH and Tubulin antibodies served as a loading control for all cell protein extracts (Abcam). WebApr 1, 2001 · Architectures of the THUMP-domain-containing proteins. The schemes are drawn approximately to scale. C4 and C4-finger are two predicted metal-chelating …

WebThe THUMP domain is named after after thiouridine synthases, methylases and PSUSs (PUBMED:11295541). The THUMP domain consists of about 110 amino acid residues. …

WebNov 18, 2024 · THUMPD3-knockout cells exhibited impaired global protein synthesis and reduced growth. Our data highlight the significance of the tRNA: m2G6/7 modification and … salesforce email field lengthWebAccording to their enzymatic activity, THUMP-related tRNA modification enzymes can be classified into five types, namely 4-thiouridine synthetase, deaminase, methyltransferase, a partner... salesforce email relay exchange onlineWebThe RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell … thinkbook 13s gen 4 amd battery lifeWebMar 21, 2024 · THUMPD3 (THUMP Domain Containing 3) is a Protein Coding gene. Diseases associated with THUMPD3 include Cerebellar Angioblastoma and Chromosome 3Pter-P25 Deletion Syndrome . Gene Ontology (GO) annotations related to this gene include RNA … thinkbook 13x windows helloWebOct 26, 2024 · THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal squamous cell carcinoma cells as revealed by transposon activation mutagenesis Masato Hayashi, Hirofumi Kawakubo, Kazumasa Fukuda, Shuhei Mayanagi, Rieko Nakamura, Koichi Suda, Testu Hayashida, Norihito Wada, … salesforce email thread idWebTHUMP domain containing 1 Symbol thumpd1 Nomenclature History Previous Names zgc:77221 Type protein_coding_gene Location Chr: 1 Mapping Details/Browsers Description Predicted to have RNA binding activity. Predicted to be involved in tRNA modification. Is expressed in female organism. Orthologous to human THUMPD1 (THUMP domain … thinkbook 13s-iwl 仕様WebThumpd1 Name THUMP domain containing 1 Synonyms 6330575P11Rik, MGC:7161 Feature Type protein coding gene IDs MGI:2444479 NCBI Gene: 233802 Alliance gene page Transcription Start Sites 1 TSS Location & Maps more Sequence Map Chr7:119314316-119320021 bp, - strand From Ensembl annotation of GRCm39 Genetic Map Chromosome … salesforce einstein knowledge